About this Book: |
|
The consecutive-competitive bromination of 1,3,5-trimethoxybenzene has been applied to static flow mixer devices described in this thesis. Mesoscale and microscale devices were tested. The bromination reaction was sensitive to mixing in all mixers tested. The best micromixer gave 1-bromo-2,4,6-trimethoxybenzene to 1,3-dibromo-2,4,6-trimethoxybenzene product ratios up to 100. The devices were also characterized using the parallel-competitive reaction of iodate and dihydrogen borate with acid. Both reactions were able to characterize the mixers with stable results at room temperature. The iodide/iodate method required multiple concentration ranges to characterize all mixers, whereas the bromination reaction method was able to characterize all mixers at a single concentration. Both methods suffer from material limitations. Bromine is not compatible with metals and reacts with methanol in the presence of light, and iodine may stick to or clog glass or fluorinated polymer devices.
|